To ensure complete regulatory compliance, ISIS’ Institutional Animal Care and Use Committee (IACUC) reviews all new protocols prior to acceptance. All work follows Good Laboratory Practice (GLP) guidelines, and the company maintains required registration with the United States Department of Agriculture, the National Institute of Health, the Food and Drug Administration, and the Drug Enforcement Administration. Both our Berkeley and San Carlos facility received full accreditation from the Association for the Assessment and Accreditation of Laboratory Animal Care (AAALAC) in 2008.