Prototype Development ISIS works hand-in-hand with your biomedical engineers and physicians/surgeons piloting studies and fine-tuning the adaptation of the prototype device. Preclinical Studies ISIS provides preclinical studies ranging from feasibility to safety and efficacy studies, including cardiovascular, orthopedic, maxillofacial, gastrointestinal, urogenital, wound healing, and dermatological. Physician and Sales Force Training ISIS trains clinical site physicians and surgeons, offering you the level of expertise you are accustomed to in your own institution. Product Concept Testing Applying its expertise in comparative medicine, ISIS assists you in adapting the product concept to an Innovative Surgery and Investigative Services setting, advising on such variables as vessel size, anatomical locations, and organ structure. Applied Comparative Medicine Expertise Experimental Surgery and Anesthesia In Vivo Models in Multiple Species Interventional Imaging Cardiovascular Neurovascular Urogenital Orthopedic Pathology ISIS applies its broad expertise and capabilities to add value at every step of the product development life cycle, facilitating progress from the benchtop to the market. At each stage of the process, ISIS provides Good Laboratory Practice (GLP) and non-GLP expertise and capabilities in comparative medicine, surgery, and pathology optimizing device design and performance. ISIS has specialized full-time veterinarians, a veterinary pathologist, along with a highly trained and experienced technical staff. Additionally, our staff is supported by consulting veterinarians and physicians with specialties in anesthesiology, cardiology, surgery, and radiology. ISIS recognizes that each project is unique, and we tailor our services to meet individual client needs. Drawing upon a wide range of in-house expertise, ISIS works with clients to design appropriate protocols, select the most suitable animal models, acquire and prepare specialized laboratory animals, and provide scientific and clinical guidance to ensure optimum outcomes. ISIS conducts GLP safety and efficacy studies as the basis for Investigational Device Exemption (IDE) submissions to the FDA. The group is well experienced in performing both acute and chronic studies in multiple species, and has helped to bring numerous novel devices and technologies successfully through this process. Non-clinical Development Services ISIS Services offers a variety of non-clinical development services to provide scientific professionals with the support they need to meet their research objectives.  Our services range from PK, Biocompatibility and Toxicology Studies to Cardiovascular Models and General Diagnostics. Read more>> Custom Polyclonal Antibody Services  ISIS Services specializes in custom polyclonal antibody production services designed to provide you with an antibody product that perfectly suits your application. We offer a wide variety of antibodies, including anti-peptide antibodies, phosphor-specific antibodies or protein antibodies. With over 25 years of experience, our specialization and expertise in this area allows us to deliver cost-effective solutions at the highest quality service while still meeting your deadline. ISIS Services has an active IACUC accreditation that regularly reviews and approves all polyclonal antisera production protocols. Our antigens are emulsified with either freunds complete adjuvant for initial injections or incomplete adjuvant for boosts. Antibody antiserums are guaranteed to be delivered within seven weeks.