At ISIS, we understand how important high-quality surgical models that meet exacting scientific and regulatory standards are to your research. Our locations in San Carlos, CA and Berkeley, CA provide the latest in experimental surgery capabilities.  With over 25 years of experience in preclinical studies, we have the specialized skills and resources to assist you in your research. Each of our state-of-the-art surgical facilities is fully equipped with ORs and support areas for preparation, necropsy and pathology support, surgery scrub, instrument preparation,  laboratory tests, and an engineering lab should your device require minor adjustments during testing. ISIS Experimental Surgical Services Proof of Concept Prototype Development Safety Efficacy Device Validation & Verification Biocompatibility Our team of highly skilled veterinary professionals is ready to guide you through the process, choosing the appropriate model and implementing the study design to optimize your opportunity for success. We offer an array of surgical services across a host of species, from small animal (mouse, rat, hamster, guinea pig, and rabbit) to larger animals (cats, dogs, goats, sheep, pigs, cattle and non-human primates).  Species selection is critical and our veterinary team will assist in the appropriate selection of your animal model to expedite the successful outcome of your studies. Our capabilities span the range from acute and chronic studies in small and large animal models such as infarct model and treatment in rodents and intracranial ventricular cannulation in swine models. Whether you need a basic research model or an entire discovery program, you can trust ISIS to be an integral part of your product development program.  ISIS has worked with clients to develop animal model systems for various device types, including: Medical Device Experience Cardiovascular Gastrointestinal Orthopedic Urogenital Drug Delivery Opthalmogic Neurologic Wound Healing Tissue Engineering Dental